Nexxt Spine Announces Development of NanoMatrixx: a Porous Bioactive Titanium Material

Nexxt Spine’s NanoMatrixx Porous Bioactive Titanium is ready to set a new standard in interbody fusion

October 12, 2015

Nexxt Spine, LLC, Founded in 2009, LLC is a is a privately held medical device company dedicated to increasing procedural efficiency and patient outcomes through development of innovative products, manufactured on the most technologically advanced platforms, and utilizing irreproachable quality standards to treat painful and debilitating spinal pathologies today announced the development of NanoMatrixx, a porous bioactive titanium material designed to participate in the intervertebral fusion process.

Nexxt Spine’s NanoMatrixx is manufactured to exacting specifications utilizing modern 3-D printing technology to replicate the cellular structure of cancellous bone. This process makes it possible to create any three dimensional complex structure or geometry with a desired modulus of elasticity that cannot be created by traditional orthopedic manufacturing processes.

Following the manufacturing process, the material undergoes a series of proprietary treatments to produce a micro and nanosurface topography which stimulates mesenchymal stem cells to differentiate into bone forming osteoblast cells that produce bone growth onto and throughout the 3-D printed material.

According to Dr. Robert L. Wertz, Director of New Product Development, “A glimpse inside of the NanoMatrixx material reveals its uniform 3-dimensional cellular architecture with a consistent 70% porosity. The cubical shaped scaffold provides an optimal biomechanical and biological environment for uninterrupted blood flow. Every surface of the NanoMatrixx material exhibits a micro and nanotextured topography that’s designed to elicit a superior osteogenic response. This allows bone to attach to the internal struts and grow entirely through the material while simultaneously providing optimal mechanical support without the stress shielding effects experienced with traditional titanium implants.

Conventional textured or coated implant surfaces only achieve bone to implant contact or on-growth; however, NanoMatrixx’s consistent open and interconnected network of pores within a specific size range have been found to be osteoconductive and osteoinductive, promoting bone on-growth and bone in-growth for total osseous integration. Bone has the potential to not only grow into the pores and around the struts, but also attach to the nanotextured strut surfaces.”

A preview of the NanoMatrixx Porous Bioactive Titanium Material will be featured at the 30th Annual North American Spine Society (NASS) Meeting, October 14- 17, 2015, in Chicago, IL. To arrange an introductory meeting with a member of our New Product Development team please contact